Protein conformation: through a lens, darkly.
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ABSTRACT: This commentary describes the study by Calleja and co-workers, who have used fluorescence resonance energy transfer between two fluorescent proteins fused to one protein kinase (protein kinase B/Akt) to reveal conformational changes in a functional protein. The findings of their study offer an intriguing insight into the behaviour of an enzyme that is essential for multiple aspects of mammalian signalling.
SUBMITTER: Insall R
PROVIDER: S-EPMC1223390 | biostudies-other | 2003 May
REPOSITORIES: biostudies-other
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