Ontology highlight
ABSTRACT:
SUBMITTER: Gauger KJ
PROVIDER: S-EPMC1241914 | biostudies-other | 2004 Apr
REPOSITORIES: biostudies-other
Gauger Kelly J KJ Kato Yoshihisa Y Haraguchi Koichi K Lehmler Hans-Joachim HJ Robertson Larry W LW Bansal Ruby R Zoeller R Thomas RT
Environmental health perspectives 20040401 5
Polychlorinated biphenyls (PCBs) are ubiquitous environmental contaminants routinely found in human and animal tissues. Developmental exposure to PCBs is associated with neuropsychologic deficits, which may be related to effects on thyroid hormone (TH) signaling in the developing brain. However, PCBs may interfere with TH signaling solely by reducing circulating levels of TH, or they may exert direct effects on TH receptors (TRs). Therefore, we tested whether maternal exposure to a commercial PC ...[more]