Ontology highlight
ABSTRACT:
SUBMITTER: Adhikary A
PROVIDER: S-EPMC1243799 | biostudies-other | 2005
REPOSITORIES: biostudies-other
Adhikary Amitava A Malkhasian Aramice Y S AY Collins Sean S Koppen Jessica J Becker David D Sevilla Michael D MD
Nucleic acids research 20051004 17
This work presents evidence that photo-excitation of guanine radical cations results in high yields of deoxyribose sugar radicals in DNA, guanine deoxyribonucleosides and deoxyribonucleotides. In dsDNA at low temperatures, formation of C1'* is observed from photo-excitation of G*+ in the 310-480 nm range with no C1'* formation observed > or =520 nm. Illumination of guanine radical cations in 2'dG, 3'-dGMP and 5'-dGMP in aqueous LiCl glasses at 143 K is found to result in remarkably high yields ( ...[more]