Spatial localisation of transcripts of the Hox-C6 gene.
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ABSTRACT:
SUBMITTER: Shimeld SM
PROVIDER: S-EPMC1259877 | biostudies-other | 1993 Dec
REPOSITORIES: biostudies-other
Publications
Spatial localisation of transcripts of the Hox-C6 gene.
Shimeld S M SM Gaunt S J SJ Coletta P L PL Geada A M AM Sharpe P T PT
Journal of anatomy 19931201
The Hox-C6 gene, in common with its Xenopus and human homologues, is organised as 3 exons with 2 distinct promoters (PRI and PRII) producing 2 different transcripts. The PRII promoter produces a 'typical' Hox transcript by splicing 2 exons separated by a 700 bp intron. The PRI promoter initiates transcription from a 3rd exon, 9 kbp 5' of PRII. This exon is spliced into the 1st exon of the PRII transcript at a point 3' of the translation start codon. This means that the predicted protein product ...[more]
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