Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Nuclear-magnetic-resonance and mass-spectral study of myxinol tetra-acetate.

ABSTRACT: Myxinol tetra-acetate was examined by both nuclear-magnetic-resonance and mass-spectral techniques. The results are compared with corresponding data for 5alpha-ranol tetra-acetate and 5alpha-cyprinol tetra-acetate. The structure deduced for myxinol tetra-acetate, 3beta,7alpha,16alpha,27-tetrahydroxy-5beta-cholestane, is in agreement with that simultaneously arrived at by Haslewood (1966).

SUBMITTER: Cross AD

PROVIDER: S-EPMC1265116 | biostudies-other | 1966 Jul

REPOSITORIES: biostudies-other

ACCESS DATA

Json Xml

Similar Datasets

Isocoproporphyrin: nuclear-magnetic-resonance-and mass-spectral methods for the determination of porphyrin structure.

Project description:The use of ;shift reagents' in the determination of n.m.r. spectra, and of reductive alkylation in combination with g.l.c.-mass spectrometry, facilitates assignment of the order of substituents in porphyrins, and the application of these new techniques to isocoproporphyrin is described.

| S-EPMC1177486 | biostudies-other

Nuclear-magnetic-resonance and mass-spectral examination of the principal bile alcohol from Catostomus commersoni and its anhydro derivative.

Project description:On the basis of i.r. and chromatographic evidence 5alpha-cholestane-3alpha,7alpha,12alpha,24xi,26-pentol(I) and 24xi,26-oxido-5alpha-cholestane-3alpha,7alpha,12alpha-triol (IV) structures have been proposed for the principal cleavage and alkaline-hydrolysis products of the bile salts from Catostomus commersoni (Anderson & Haslewood, 1969). N.m.r.- and mass-spectral analyses of these substances and the tetra- (II) and penta-acetate (III) derivatives of (I) provided supporting evidence for the structural assignments.

| S-EPMC1185403 | biostudies-other

Collagen cross-links. A mass-spectrometric and 1H- and 13C-nuclear-magnetic-resonance study.

Project description:1. The structure of a tetrafunctional cross-link (compound C) isolated from borohydride-reduced cow skin collagen has been determined by the combined use of mass spectrometry and (1)H and (13)C n.m.r. spectroscopy. 2. A new technique, of potentially wide applicability, is described for the mass-spectrometric determination of functional groups. 3. Detailed study of protonation shifts in the (13)C spectrum has allowed an unambiguous assignment of the exact structural relationship of the component parts of the molecule. 4. New interpretations of existing data on this molecule are given.

| S-EPMC1165902 | biostudies-other

Purity Assessment of Dinotefuran Using Mass Balance and Quantitative Nuclear Magnetic Resonance.

Project description:Dinotefuran (DNT) belongs to the third-generation neonicotinoid pesticides, which are among the most common residuals in a variety of food commodities. To guarantee accurate quantification and traceability of results in food samples, certified reference materials (CRMs) are the indispensable benchmark. In this work, a DNT CRM was characterized and its purity was assessed by two independent methods, including mass balance (MB) and quantitative nuclear magnetic resonance spectroscopy (qNMR). The mass fraction of moisture was 0.33 mg/g, the inorganic impurity was 0.01 mg/g, and no detectable organic solvent was detected. Benzoic acid was chosen as the internal standard for qNMR. Its mass fraction was 997.9 mg/g and 992.9 mg/g by MB and qNMR, respectively. Eventually, the DNT CRM was assigned a mass fraction of 995 mg/g, with expanded uncertainty of 5 mg/g (k = 2). This CRM can be used to prepare calibrant solutions and is applicable to national routine monitoring of DNT residuals in agro-products and food.

| S-EPMC10179808 | biostudies-literature

Electrospray ionization mass spectrometry and nuclear magnetic resonance spectroscopy data for anacardic acid derivatives.

Project description:The data presented here are related to the research paper entitled "Janohigenins: Long-chain anacardic acid derivatives with neuroprotective activity from Ophiopogon japonicus seeds" (Ohta et al., 2021). In this data article, we provide electrospray ionization mass spectrometry (ESIMS) and 1D and 2D nuclear magnetic resonance (NMR) spectroscopy data of four new anacardic acid derivatives, janohigenins isolated from the seeds of Ophiopogon japonicus.

| S-EPMC8857442 | biostudies-literature

Super-Resolved Nuclear Magnetic Resonance Spectroscopy.

Project description:We present a novel method that breaks the resolution barrier in nuclear magnetic resonance (NMR) spectroscopy, allowing one to accurately estimate the chemical shift values of highly overlapping or broadened peaks. This problem is routinely encountered in NMR when peaks have large linewidths due to rapidly decaying signals, hindering its application. We address this problem based on the notion of finite-rate-of-innovation (FRI) sampling, which is based on the premise that signals such as the NMR signal, can be accurately reconstructed using fewer measurements than that required by existing approaches. The FRI approach leads to super-resolution, beyond the limits of contemporary NMR techniques. Using this method, we could measure for the first time small changes in chemical shifts during the formation of a Gold nanorod-protein complex, facilitating the quantification of the strength of such interactions. The method thus opens up new possibilities for the application and acceleration of multidimensional NMR spectroscopy across a wide range of systems.

| S-EPMC5575056 | biostudies-literature

Ultrafast diffusion exchange nuclear magnetic resonance.

Project description:The exchange of molecules between different physical or chemical environments due to diffusion or chemical transformations has a crucial role in a plethora of fundamental processes such as breathing, protein folding, chemical reactions and catalysis. Here, we introduce a method for a single-scan, ultrafast NMR analysis of molecular exchange based on the diffusion coefficient contrast. The method shortens the experiment time by one to four orders of magnitude. Consequently, it opens the way for high sensitivity quantification of important transient physical and chemical exchange processes such as in cellular metabolism. As a proof of principle, we demonstrate that the method reveals the structure of aggregates formed by surfactants relevant to aerosol research.

| S-EPMC7319991 | biostudies-literature

Nuclear magnetic resonance captures the elusive.

Project description:Innovative nuclear magnetic resonance approaches have emerged as outstanding means of tracking down functionally important properties of biomolecular assemblies that evade detection. These enigmatic attributes include dynamic equilibria with very lightly populated excited states and structures of complexes obscured by slow tumbling in solution.

| S-EPMC2920670 | biostudies-literature

Nuclear magnetic resonance diffraction with subangstrom precision.

Project description:We have combined ultrasensitive force-based spin detection with high-fidelity spin control to achieve NMR diffraction (NMRd) measurement of ~2 million [Formula: see text]P spins in a [Formula: see text] volume of an indium-phosphide (InP) nanowire. NMRd is a technique originally proposed for studying the structure of periodic arrangements of spins, with complete access to the spectroscopic capabilities of NMR. We describe two experiments that realize NMRd detection with subangstrom precision. In the first experiment, we encode a nanometer-scale spatial modulation of the z-axis magnetization of [Formula: see text]P spins and detect the period and position of the modulation with a precision of <0.8 Å. In the second experiment, we demonstrate an interferometric technique, utilizing NMRd, to detect an angstrom-scale displacement of the InP sample with a precision of 0.07 Å. The diffraction-based techniques developed in this work extend the Fourier-encoding capabilities of NMR to the angstrom scale and demonstrate the potential of NMRd as a tool for probing the structure and dynamics of nanocrystalline materials.

| S-EPMC9546613 | biostudies-literature

Cellular solid-state nuclear magnetic resonance spectroscopy.

Project description:Decrypting the structure, function, and molecular interactions of complex molecular machines in their cellular context and at atomic resolution is of prime importance for understanding fundamental physiological processes. Nuclear magnetic resonance is a well-established imaging method that can visualize cellular entities at the micrometer scale and can be used to obtain 3D atomic structures under in vitro conditions. Here, we introduce a solid-state NMR approach that provides atomic level insights into cell-associated molecular components. By combining dedicated protein production and labeling schemes with tailored solid-state NMR pulse methods, we obtained structural information of a recombinant integral membrane protein and the major endogenous molecular components in a bacterial environment. Our approach permits studying entire cellular compartments as well as cell-associated proteins at the same time and at atomic resolution.

| S-EPMC3323964 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data