Ontology highlight
ABSTRACT:
SUBMITTER: Thompson PM
PROVIDER: S-EPMC1266080 | biostudies-other | 2005 Oct
REPOSITORIES: biostudies-other
Thompson Paul M PM Dutton Rebecca A RA Hayashi Kiralee M KM Toga Arthur W AW Lopez Oscar L OL Aizenstein Howard J HJ Becker James T JT
Proceedings of the National Academy of Sciences of the United States of America 20051014 43
HIV/AIDS infection is the fourth leading cause of death worldwide, and one in every 100 adults aged 15-49 years is HIV-infected. Forty percent of AIDS patients suffer from neurological symptoms, but the selective profile of damage caused by HIV in the brain is not well understood. Here, we report 3D maps revealing how AIDS affects the human cerebral cortex, identifying the most vulnerable regions and where deficits link with cognitive decline and immune-system suppression. With high-resolution b ...[more]