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[35S]thiosulphate oxidation by rat liver mitochondria in the presence of glutathione.


ABSTRACT: 1. Rat liver mitochondria incubated in oxygen with glutathione and [(35)S]-thiosulphate produced labelled sulphate. 2. Inner-labelled thiosulphate (S.(35)SO(3))(2-) was converted into [(35)S]sulphate more rapidly than outer-labelled thiosulphate ((35)S.SO(3))(2-). 3. Thiosulphate labelled in both sulphur atoms was formed during ((35)S.SO(3))(2-) oxidation; the outer sulphur atom before oxidation to sulphate was incorporated into the inner position. 4. A thiosulphate cycle in the metabolic pathway of sulphate formation in animal tissues is discussed.

SUBMITTER: Koj A 

PROVIDER: S-EPMC1270484 | biostudies-other | 1967 Jun

REPOSITORIES: biostudies-other

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