Ontology highlight
ABSTRACT:
SUBMITTER: Vivian JT
PROVIDER: S-EPMC1301402 | biostudies-other | 2001 May
REPOSITORIES: biostudies-other
Biophysical journal 20010501 5
Tryptophan fluorescence wavelength is widely used as a tool to monitor changes in proteins and to make inferences regarding local structure and dynamics. We have predicted the fluorescence wavelengths of 19 tryptophans in 16 proteins, starting with crystal structures and using a hybrid quantum mechanical-classical molecular dynamics method with the assumption that only electrostatic interactions of the tryptophan ring electron density with the surrounding protein and solvent affect the transitio ...[more]