Cytokine gene expression in Helicobacter pylori associated antral gastritis.
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ABSTRACT:
SUBMITTER: Moss SF
PROVIDER: S-EPMC1375613 | biostudies-other | 1994 Nov
REPOSITORIES: biostudies-other
Publications
Cytokine gene expression in Helicobacter pylori associated antral gastritis.
Moss S F SF Legon S S Davies J J Calam J J
Gut 19941101 11
Infection of the gastric antrum by Helicobacter pylori is characterised by a cellular inflammatory infiltrate. Whether cytokines are involved in the pathogenesis of this gastritis has been investigated by studying the effect of eradicating H pylori on the expression of genes encoding the cytokines interleukin 8 (IL-8) and tumour necrosis factor alpha (TNF-alpha) in the antral mucosa. Gastric antral biopsy specimens were taken from nine patients with duodenal ulcers and cytokine transcripts were ...[more]
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