Ontology highlight
ABSTRACT:
SUBMITTER: Gorski B
PROVIDER: S-EPMC1378051 | biostudies-other | 2000 Jun
REPOSITORIES: biostudies-other
Górski B B Byrski T T Huzarski T T Jakubowska A A Menkiszak J J Gronwald J J Pluzańska A A Bebenek M M Fischer-Maliszewska L L Grzybowska E E Narod S A SA Lubiński J J
American journal of human genetics 20000428 6
We have undertaken a hospital-based study, to identify possible BRCA1 and BRCA2 founder mutations in the Polish population. The study group consisted of 66 Polish families with cancer who have at least three related females affected with breast or ovarian cancer and who had cancer diagnosed, in at least one of the three affected females, at age <50 years. A total of 26 families had both breast and ovarian cancers, 4 families had ovarian cancers only, and 36 families had breast cancers only. Geno ...[more]