Ontology highlight
ABSTRACT:
SUBMITTER: Emery P
PROVIDER: S-EPMC145730 | biostudies-other | 1996 Mar
REPOSITORIES: biostudies-other
Emery P P Durand B B Mach B B Reith W W
Nucleic acids research 19960301 5
Until recently, the RFX family of DNA binding proteins consisted exclusively of four mammalian members (RFX1-RFX4) characterized by a novel highly conserved DNA binding domain. Strong conservation of this DNA binding domain precluded a precise definition of the motif required for DNA binding. In addition, the biological systems in which these RFX proteins are implicated remained obscure. The recent identification of four new RFX genes has now shed light on the evolutionary conservation of the RF ...[more]