Ontology highlight
ABSTRACT:
SUBMITTER: Ohnacker M
PROVIDER: S-EPMC145984 | biostudies-other | 1996 Jul
REPOSITORIES: biostudies-other
Ohnacker M M Minvielle-Sebastia L L Keller W W
Nucleic acids research 19960701 13
We have isolated the poly(A) polymerase (PAP) encoding gene pla1 [for poly(A) polymerase] from the fission yeast Schizosaccharomyces pombe. Protein sequence alignments with other poly(A) polymerases reveal that pla1 is more closely related to Saccharomyces cerevisiae PAP than to bovine PAP. The two yeast poly(A) polymerases share significant sequence homology not only in the generally conserved N-terminal part but also in the C-terminus. Furthermore, pla1 rescues a S. cerevisiae PAP1 disruption ...[more]