Ontology highlight
ABSTRACT:
SUBMITTER: McConnell TJ
PROVIDER: S-EPMC1460285 | biostudies-other | 1998 Aug
REPOSITORIES: biostudies-other
McConnell T J TJ Godwin U B UB Norton S F SF Nairn R S RS Kazianis S S Morizot D C DC
Genetics 19980801 4
We have isolated two major histocompatibility complex (MHC) class II B genes from the inbred fish strain Xiphophorus maculatus Jp 163 A. We mapped one of these genes, designated here as DXB, to linkage group III, linked to a malic enzyme locus, also syntenic with human and mouse MHC. Comparison of genomic and cDNA clones shows the gene consists of six exons and five introns. The encoded beta1 domain has three amino acids deleted and a cytoplasmic tail nine amino acids longer than in other teleos ...[more]