Molecular evolution of the Cecropin multigene family in Drosophila. functional genes vs. pseudogenes.
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ABSTRACT:
SUBMITTER: Ramos-Onsins S
PROVIDER: S-EPMC1460299 | biostudies-other | 1998 Sep
REPOSITORIES: biostudies-other
Publications
Molecular evolution of the Cecropin multigene family in Drosophila. functional genes vs. pseudogenes.
Genetics 19980901 1
Approximately 4 kb of the Cecropin cluster region have been sequenced in nine lines of Drosophila melanogaster and one line of the sibling species D. simulans, D. mauritiana, and D. sechellia. This region includes three functional genes (CecA1, CecA2, and CecB), which are involved in the insect immune response, and two pseudogenes (CecPsi1 and CecPsi2). The level of silent polymorphism in the three Cec genes is rather high (0.028), and there is no excess of nonsynonymous polymorphism. There is n ...[more]
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