Ontology highlight
ABSTRACT:
SUBMITTER: Kern AD
PROVIDER: S-EPMC1462383 | biostudies-other | 2002 Dec
REPOSITORIES: biostudies-other
Kern Andrew D AD Jones Corbin D CD Begun David J DJ
Genetics 20021201 4
Selective fixation of beneficial mutations reduces levels of linked, neutral variation. The magnitude of this "hitchhiking effect" is determined by the strength of selection and the recombination rate between selected and neutral sites. Thus, depending on the values of these parameters and the frequency with which directional selection occurs, the genomic scale over which directional selection reduces levels of linked variation may vary widely. Here we present a permutation-based analysis of nuc ...[more]