Genetic diversity in yeast assessed with whole-genome oligonucleotide arrays.
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ABSTRACT:
SUBMITTER: Winzeler EA
PROVIDER: S-EPMC1462430 | biostudies-other | 2003 Jan
REPOSITORIES: biostudies-other
Publications
Genetic diversity in yeast assessed with whole-genome oligonucleotide arrays.
Winzeler Elizabeth A EA Castillo-Davis Cristian I CI Oshiro Guy G Liang David D Richards Daniel R DR Zhou Yingyao Y Hartl Daniel L DL
Genetics 20030101 1
The availability of a complete genome sequence allows the detailed study of intraspecies variability. Here we use high-density oligonucleotide arrays to discover 11,115 single-feature polymorphisms (SFPs) existing in one or more of 14 different yeast strains. We use these SFPs to define regions of genetic identity between common laboratory strains of yeast. We assess the genome-wide distribution of genetic variation on the basis of this yeast population. We find that genome variability is biased ...[more]
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