Ontology highlight
ABSTRACT:
SUBMITTER: Selvamurugan N
PROVIDER: S-EPMC146614 | biostudies-other | 1997 Apr
REPOSITORIES: biostudies-other
Selvamurugan N N Joost O H OH Haas E S ES Brown J W JW Galvin N J NJ Eliceiri G L GL
Nucleic acids research 19970401 8
Three human small nucleolar RNAs (snoRNAs), E1, E2 and E3, were reported earlier that have unique sequences, interact directly with unique segments of pre-rRNA in vivo and are encoded in introns of protein genes. In the present report, human and frog E1, E2 and E3 RNAs injected into the cytoplasm of frog oocytes migrated to the nucleus and specifically to the nucleolus. This indicates that the nucleolar and nuclear localization signals of these snoRNAs reside within their evolutionarily conserve ...[more]