Ontology highlight
ABSTRACT:
SUBMITTER: Charlesworth A
PROVIDER: S-EPMC1500856 | biostudies-other | 2006 Jun
REPOSITORIES: biostudies-other
Charlesworth Amanda A Wilczynska Anna A Thampi Prajitha P Cox Linda L LL MacNicol Angus M AM
The EMBO journal 20060608 12
A strict temporal order of maternal mRNA translation is essential for meiotic cell cycle progression in oocytes of the frog Xenopus laevis. The molecular mechanisms controlling the ordered pattern of mRNA translational activation have not been elucidated. We report a novel role for the neural stem cell regulatory protein, Musashi, in controlling the translational activation of the mRNA encoding the Mos proto-oncogene during meiotic cell cycle progression. We demonstrate that Musashi interacts sp ...[more]