Ontology highlight
ABSTRACT:
SUBMITTER: Yao F
PROVIDER: S-EPMC1538803 | biostudies-other | 2006 Jul
REPOSITORIES: biostudies-other
Yao Fengxia F Zhang Ruifang R Zhu Zanhua Z Xia Kun K Liu Chunyu C
Nucleic acids research 20060701 Web Server issue
In searching for susceptibility genes, both positional cloning and candidate gene strategies have been helpful. Mutation screening is one of the many technologies that have been implemented in order to identify mutations or polymorphisms in candidate genes or genomic regions. Since human genome sequence is available, PCR-direct sequencing is one of the major methods for mutation screening or resequencing. Unfortunately, assay design can be laborious if multiple genes or large regions need to be ...[more]