Ontology highlight
ABSTRACT:
SUBMITTER: Imamura M
PROVIDER: S-EPMC1564388 | biostudies-other | 2006 Jul
REPOSITORIES: biostudies-other
Imamura Masanori M Miura Kyoko K Iwabuchi Kumiko K Ichisaka Tomoko T Nakagawa Masato M Lee Jiyoung J Kanatsu-Shinohara Mito M Shinohara Takashi T Yamanaka Shinya S
BMC developmental biology 20060721
<h4>Background</h4>We previously identified a set of genes called ECATs (ES cell-associated transcripts) that are expressed at high levels in mouse ES cells. Here, we examine the expression and DNA methylation of ECATs in somatic cells and germ cells.<h4>Results</h4>In all ECATs examined, the promoter region had low methylation levels in ES cells, but higher levels in somatic cells. In contrast, in spite of their lack of pluripotency, male germline stem (GS) cells expressed most ECATs and exhibi ...[more]