Ontology highlight
ABSTRACT:
SUBMITTER: Hegmans JP
PROVIDER: S-EPMC1615654 | biostudies-other | 2004 May
REPOSITORIES: biostudies-other
Hegmans Joost P J J JP Bard Martin P L MP Hemmes Annabrita A Luider Theo M TM Kleijmeer Monique J MJ Prins Jan-Bas JB Zitvogel Laurence L Burgers Sjaak A SA Hoogsteden Henk C HC Lambrecht Bart N BN
The American journal of pathology 20040501 5
Exosomes are small membrane vesicles secreted into the extracellular compartment by exocytosis. Tumor exosomes may be involved in the sampling of antigens to antigen presenting cells or as decoys allowing the tumor to escape immune-directed destruction. The proteins present in exosomes secreted by tumor cells have been poorly defined. This study describes the protein composition of mesothelioma cell-derived exosomes in more detail. After electrophoresis of exosome preparations, matrix-assisted l ...[more]