Ontology highlight
ABSTRACT:
SUBMITTER: Newton SM
PROVIDER: S-EPMC1622867 | biostudies-other | 2006 Oct
REPOSITORIES: biostudies-other
Proceedings of the National Academy of Sciences of the United States of America 20061006 42
Six major lineages of Mycobacterium tuberculosis appear preferentially transmitted amongst distinct ethnic groups. We identified a deletion affecting Rv1519 in CH, a strain isolated from a large outbreak in Leicester U.K., that coincidentally defines the East African-Indian lineage matching a major ethnic group in this city. In broth media, CH grew less rapidly and was less acidic and H2O2-tolerant than reference sequenced strains (CDC1551 and H37Rv). Nevertheless, CH was not impaired in its abi ...[more]