Ontology highlight
ABSTRACT:
SUBMITTER: Vila J
PROVIDER: S-EPMC162713 | biostudies-other | 1995 May
REPOSITORIES: biostudies-other
Vila J J Ruiz J J Goñi P P Marcos A A Jimenez de Anta T T
Antimicrobial agents and chemotherapy 19950501 5
The gyrA gene mutations associated with quinolone resistance were determined in 21 epidemiologically unrelated clinical isolates of Acinetobacter baumannii. Our studies highlight the conserved sequences in the quinolone resistance-determining region of the gyrA gene from A. baumannii and other bacteria. All 15 isolates for which the MIC of ciprofloxacin is > or = 4 micrograms/ml showed a change at Ser-83 to Leu. Six strains for which the MIC of ciprofloxacin is 1 microgram/ml did not show any ch ...[more]