Ontology highlight
ABSTRACT:
SUBMITTER: Niga T
PROVIDER: S-EPMC164002 | biostudies-other | 1997 Aug
REPOSITORIES: biostudies-other
Niga T T Yoshida H H Hattori H H Nakamura S S Ito H H
Antimicrobial agents and chemotherapy 19970801 8
In a study of the quinolone resistance genes in Staphylococcus aureus, a recG homolog was cloned as a gene affecting quinolone susceptibility. Sequencing analysis revealed that the gene consists of 2,061 nucleotides and encodes a 686-amino-acid polypeptide, which shows 38, 39, and 50% amino acid identity with the RecGs of Escherichia coli, Haemophilus influenzae, and Streptococcus pneumoniae, respectively. Seven helicase motifs are well conserved in the gene product. A plasmid carrying the gene ...[more]