Ontology highlight
ABSTRACT:
SUBMITTER: Graessle S
PROVIDER: S-EPMC168364 | biostudies-other | 1997 Feb
REPOSITORIES: biostudies-other
Graessle S S Haas H H Friedlin E E Kürnsteiner H H Stöffler G G Redl B B
Applied and environmental microbiology 19970201 2
A system for regulated heterologous gene expression in the filamentous fungus Penicillium chrysogenum was established. This is the first heterologous expression system to be developed for this organism. Expression of a recombinant fungal xylanase gene (xylp) and the cDNA for the human tear lipocalin (LCNI) was achieved by placing the encoding sequences under the control of the repressible acid phosphatase gene (phoA) promoter of P. chrysogenum. Secreted recombinant proteins were detected in the ...[more]