Evolution of Emx genes and brain development in vertebrates.
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ABSTRACT:
SUBMITTER: Patarnello T
PROVIDER: S-EPMC1688749 | biostudies-other | 1997 Dec
REPOSITORIES: biostudies-other
Publications
Evolution of Emx genes and brain development in vertebrates.
Patarnello T T Bargelloni L L Boncinelli E E Spada F F Pannese M M Broccoli V V
Proceedings. Biological sciences 19971201 1389
Emx1 and Emx2 genes are known to be involved in mammalian forebrain development. In order to investigate the evolution of the Emx gene family in vertebrates, a phylogenetic analysis was carried out on the Emx genes sequenced in man, mice, frogs, coelacanths and zebrafish. The results demonstrated the existence of two clades (Emx1 and Emx2), each grouping one of the two genes of the investigated taxa. The only exception was the zebrafish Emx1-like gene which turned out to be a sister group to bot ...[more]
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