HFE gene mutation and transferrin saturation in very low birthweight infants.
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ABSTRACT:
SUBMITTER: Maier RF
PROVIDER: S-EPMC1720994 | biostudies-other | 1999 Sep
REPOSITORIES: biostudies-other
Publications
HFE gene mutation and transferrin saturation in very low birthweight infants.
Maier R F RF Witt H H Bührer C C Mönch E E Köttgen E E
Archives of disease in childhood. Fetal and neonatal edition 19990901 2
<h4>Aim</h4>To determine if there is an association between high transferrin saturation and the C282Y HFE gene mutation in very low birthweight (VLBW) infants.<h4>Methods</h4>One hundred and forty three VLBW infants receiving recombinant erythropoietin and 3 to 9 mg/kg/day of enteral iron were studied. Genomic DNA was extracted from filter paper cards. The C282Y mutation was determined by restriction fragment length polymorphism analysis.<h4>Results</h4>Six infants were heterozygous for the muta ...[more]
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