Ocular coloboma: a reassessment in the age of molecular neuroscience.
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ABSTRACT:
SUBMITTER: Gregory-Evans CY
PROVIDER: S-EPMC1735648 | biostudies-other | 2004 Dec
REPOSITORIES: biostudies-other
Publications
Ocular coloboma: a reassessment in the age of molecular neuroscience.
Gregory-Evans C Y CY Williams M J MJ Halford S S Gregory-Evans K K
Journal of medical genetics 20041201 12
Congenital colobomata of the eye are important causes of childhood visual impairment and blindness. Ocular coloboma can be seen in isolation and in an impressive number of multisystem syndromes, where the eye phenotype is often seen in association with severe neurological or craniofacial anomalies or other systemic developmental defects. Several studies have shown that, in addition to inheritance, environmental influences may be causative factors. Through work to identify genes underlying inheri ...[more]
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