Ontology highlight
ABSTRACT:
SUBMITTER: Karita M
PROVIDER: S-EPMC175598 | biostudies-other | 1997 Oct
REPOSITORIES: biostudies-other
Karita M M Etterbeek M L ML Forsyth M H MH Tummuru M K MK Blaser M J MJ
Infection and immunity 19971001 10
Helicobacter pylori colonizes the human gastric mucosa and causes gastritis, ulceration, or gastric cancer. A previously uncharacterized region of the H. pylori genome was identified and sequenced. This region includes a putative operon containing three open reading frames termed gidA (1,866 bp), dapE (1,167 bp), and orf2 (753 bp); the gidA and dapE products are highly homologous to other bacterial proteins. In E. coli, dapE encodes N-succinyl-L-diaminopimelic acid desuccinylase, which catalyzes ...[more]