Ontology highlight
ABSTRACT:
SUBMITTER: Oguiza JA
PROVIDER: S-EPMC176612 | biostudies-other | 1995 Jan
REPOSITORIES: biostudies-other
Oguiza J A JA Tao X X Marcos A T AT Martín J F JF Murphy J R JR
Journal of bacteriology 19950101 2
A homolog of the Corynebacterium diphtheriae dtxR gene was isolated from Brevibacterium lactofermentum. The product of the B. lactofermentum dtxR gene was immunoreactive with polyclonal anti-DtxR antibodies and functioned as an iron-activated repressor capable of regulating the expression of beta-galactosidase from a diphtheria tox promoter/operator transcriptional fusion in recombinant Escherichia coli. The extents of induction by increasing concentrations of the chelator 2,2'-dipyridyl were id ...[more]