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Mutations in GltC that increase Bacillus subtilis gltA expression.

ABSTRACT: Mutants with altered forms of GltC, a positive LysR-type regulator of Bacillus subtilis glutamate synthase gene expression, were isolated. The mutant GltC proteins stimulated expression from the wild-type gltA promoter region 1.5- to 2.0-fold and from mutant promoter regions up to 80-fold. Moreover, expression of gltA became much less dependent on a nitrogen source-associated signal.

SUBMITTER: Belitsky BR

PROVIDER: S-EPMC177382 | biostudies-other | 1995 Oct

REPOSITORIES: biostudies-other

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Mutations in GltC that increase Bacillus subtilis gltA expression.

Belitsky B R BR Sonenshein A L AL

Journal of bacteriology 19951001 19

Mutants with altered forms of GltC, a positive LysR-type regulator of Bacillus subtilis glutamate synthase gene expression, were isolated. The mutant GltC proteins stimulated expression from the wild-type gltA promoter region 1.5- to 2.0-fold and from mutant promoter regions up to 80-fold. Moreover, expression of gltA became much less dependent on a nitrogen source-associated signal. ...[more]

PMID: 7559360

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