Construction and characterization of a fimZ mutant of Salmonella typhimurium.
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ABSTRACT:
SUBMITTER: Yeh KS
PROVIDER: S-EPMC177554 | biostudies-other | 1995 Dec
REPOSITORIES: biostudies-other
Publications
Construction and characterization of a fimZ mutant of Salmonella typhimurium.
Yeh K S KS Hancox L S LS Clegg S S
Journal of bacteriology 19951201 23
The Salmonella typhimurium fimA gene is controlled by several ancillary fim genes. One of these genes, fimZ, appears to be involved in increasing the expression of fimA. A fimZ mutant of S. typhimurium was constructed by allelic exchange, and this mutant was found to be nonfimbriate. The fimZ mutant demonstrated decreased levels of fimA expression compared with the parental strain when both were grown under conditions favoring fimbrial expression. An examination of the predicted amino acid seque ...[more]
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