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A two-component response regulator, gltR, is required for glucose transport activity in Pseudomonas aeruginosa PAO1.


ABSTRACT: A 729-bp open reading frame (gltR) was identified in Pseudomonas aeruginosa PAO1 that encodes a product homologous to the two-component response regulator family of proteins. Disruption of gltR caused loss of glucose transport activity. Restoration of gltR resulted in wild-type levels of glucose transport. These findings indicate that gltR is required for expression of the glucose transport system in P. aeruginosa.

SUBMITTER: Sage AE 

PROVIDER: S-EPMC178468 | biostudies-other | 1996 Oct

REPOSITORIES: biostudies-other

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A two-component response regulator, gltR, is required for glucose transport activity in Pseudomonas aeruginosa PAO1.

Sage A E AE   Proctor W D WD   Phibbs P V PV  

Journal of bacteriology 19961001 20


A 729-bp open reading frame (gltR) was identified in Pseudomonas aeruginosa PAO1 that encodes a product homologous to the two-component response regulator family of proteins. Disruption of gltR caused loss of glucose transport activity. Restoration of gltR resulted in wild-type levels of glucose transport. These findings indicate that gltR is required for expression of the glucose transport system in P. aeruginosa. ...[more]

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