A novel Arthrobacter beta-galactosidase with homology to eucaryotic beta-galactosidases.
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ABSTRACT:
SUBMITTER: Gutshall K
PROVIDER: S-EPMC179077 | biostudies-other | 1997 May
REPOSITORIES: biostudies-other
Publications
A novel Arthrobacter beta-galactosidase with homology to eucaryotic beta-galactosidases.
Gutshall K K Wang K K Brenchley J E JE
Journal of bacteriology 19970501 9
An Arthrobacter beta-galactosidase has homology with the lysosomal acid beta-galactosidases from humans and mice and with a Xanthomonas manihotis enzyme. Phylogenetic analysis of the deduced amino acid sequence showed an unusual pattern, with this procaryotic enzyme clustering within the animal clade. The gene encodes a subunit of 52 kDa, and the enzyme appears to be active as a dimer. The enzyme hydrolyzed substrates with either a beta-1,4 or a beta-1,3 linkage. ...[more]
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