Characterization of cp18, a naturally truncated member of the cp32 family of Borrelia burgdorferi plasmids.
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ABSTRACT:
SUBMITTER: Stevenson B
PROVIDER: S-EPMC179251 | biostudies-other | 1997 Jul
REPOSITORIES: biostudies-other
Publications
Characterization of cp18, a naturally truncated member of the cp32 family of Borrelia burgdorferi plasmids.
Stevenson B B Casjens S S van Vugt R R Porcella S F SF Tilly K K Bono J L JL Rosa P P
Journal of bacteriology 19970701 13
We have mapped the genes encoding the antigenic lipoproteins OspE and OspF to an approximately 18-kb circular plasmid in Borrelia burgdorferi N40. Sequencing and restriction mapping have revealed that this plasmid, cp18, is homologous to an 18-kb region of the cp32 circular plasmids found in the Lyme disease spirochetes. Our data show that cp18 may have arisen from an ancestral cp32 plasmid by deletion of a 14-kb region of DNA, indicating that a significant portion of the cp32 plasmid is not ess ...[more]
Similar Datasets
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