Ontology highlight
ABSTRACT:
SUBMITTER: Riordan NH
PROVIDER: S-EPMC1796850 | biostudies-other | 2007 Jan
REPOSITORIES: biostudies-other
Riordan Neil H NH Chan Kyle K Marleau Annette M AM Ichim Thomas E TE
Journal of translational medicine 20070130
Cord blood is currently used as an alternative to bone marrow as a source of stem cells for hematopoietic reconstitution after ablation. It is also under intense preclinical investigation for a variety of indications ranging from stroke, to limb ischemia, to myocardial regeneration. A major drawback in the current use of cord blood is that substantial morbidity and mortality are associated with pre-transplant ablation of the recipient hematopoietic system. Here we raise the possibility that due ...[more]