Cloning of the RHO1 gene from Candida albicans and its regulation of beta-1,3-glucan synthesis.
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ABSTRACT:
SUBMITTER: Kondoh O
PROVIDER: S-EPMC179736 | biostudies-other | 1997 Dec
REPOSITORIES: biostudies-other
Publications
Cloning of the RHO1 gene from Candida albicans and its regulation of beta-1,3-glucan synthesis.
Kondoh O O Tachibana Y Y Ohya Y Y Arisawa M M Watanabe T T
Journal of bacteriology 19971201 24
The Saccharomyces cerevisiae RHO1 gene encodes a low-molecular-weight GTPase. One of its recently identified functions is the regulation of beta-1,3-glucan synthase, which synthesizes the main component of the fungal cell wall (J. Drgonova et al., Science 272:277-279, 1996; T. Mazur and W. Baginsky, J. Biol. Chem. 271:14604-14609, 1996; and H. Qadota et al., Science 272:279-281, 1996). From the opportunistic pathogenic fungus Candida albicans, we cloned the RHO1 gene by the PCR and cross-hybridi ...[more]
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