Ontology highlight
ABSTRACT:
SUBMITTER: Madej T
PROVIDER: S-EPMC1852803 | biostudies-other | 2007 Apr
REPOSITORIES: biostudies-other
Madej Thomas T Panchenko Anna R AR Chen Jie J Bryant Stephen H SH
BMC structural biology 20070410
<h4>Background</h4>To discover remote evolutionary relationships and functional similarities between proteins, biologists rely on comparative sequence analysis, and when structures are available, on structural alignments and various measures of structural similarity. The measures/scores that have most commonly been used for this purpose include: alignment length, percent sequence identity, superposition RMSD and their different combinations. More recently, we have introduced the "Homologous core ...[more]