Ontology highlight
ABSTRACT:
SUBMITTER: McCord RP
PROVIDER: S-EPMC1865582 | biostudies-other | 2007
REPOSITORIES: biostudies-other
McCord Rachel Patton RP Berger Michael F MF Philippakis Anthony A AA Bulyk Martha L ML
Molecular systems biology 20070417
Numerous genomic and proteomic datasets are permitting the elucidation of transcriptional regulatory networks in the yeast Saccharomyces cerevisiae. However, predicting the condition dependence of regulatory network interactions has been challenging, because most protein-DNA interactions identified in vivo are from assays performed in one or a few cellular states. Here, we present a novel method to predict the condition-specific functions of S. cerevisiae transcription factors (TFs) by integrati ...[more]