Genetic testing for polyposis: practical and ethical aspects.
Ontology highlight
ABSTRACT:
SUBMITTER: Jarvinen HJ
PROVIDER: S-EPMC1867748 | biostudies-other | 2003 May
REPOSITORIES: biostudies-other
Publications
The three autosomal dominant inherited polyposis syndromes, familial adenomatous polyposis, juvenile polyposis, and Peutz-Jeghers polyposis predispose to colorectal cancer as does hereditary non-polyposis colorectal cancer syndrome. Uncovering the genetic background of these four cancer traits provides the possibility for genetic testing of the family members of an affected patient. Before testing identification of the underlying family specific pathogenic mutation is mandatory. This is possible ...[more]
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