Ontology highlight
ABSTRACT:
SUBMITTER: Godeny EK
PROVIDER: S-EPMC188954 | biostudies-other | 1995 Apr
REPOSITORIES: biostudies-other
Godeny E K EK Zeng L L Smith S L SL Brinton M A MA
Journal of virology 19950401 4
The 3' end of the simian hemorrhagic fever virus (SHFV) single-stranded RNA genome was cloned and sequenced. Adjacent to the 3' poly(A) tract, we identified a 76-nucleotide noncoding region preceded by two overlapping reading frames (ORFs). The ultimate 3' ORF of the viral genome encodes the capsid protein, and the penultimate ORF encodes the smallest SHFV envelope protein. These two ORFs overlap each other by 26 nucleotides. Northern (RNA) blot hybridization analyses of cytoplasmic RNA extracts ...[more]