Association of mouse fibrinogen-like protein with murine hepatitis virus-induced prothrombinase activity.
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ABSTRACT:
SUBMITTER: Parr RL
PROVIDER: S-EPMC189320 | biostudies-other | 1995 Aug
REPOSITORIES: biostudies-other
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Association of mouse fibrinogen-like protein with murine hepatitis virus-induced prothrombinase activity.
Parr R L RL Fung L L Reneker J J Myers-Mason N N Leibowitz J L JL Levy G G
Journal of virology 19950801 8
Previously, we demonstrated induction of a unique macrophage prothrombinase during infection of BALB/cJ mice by mouse hepatitis virus strain 3 (MHV-3). By immunologic screening, a clone representing this prothrombinase was isolated from a cDNA library and sequenced. The sequence identified this clone as representing part of a gene, musfiblp, that encodes a fibrinogen-like protein. Six additional clones were isolated, and one clone, p11-3-1, encompassed the entire coding region of musfiblp. Murin ...[more]
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