Ontology highlight
ABSTRACT:
SUBMITTER: MacDonald MR
PROVIDER: S-EPMC191229 | biostudies-other | 1997 Feb
REPOSITORIES: biostudies-other
MacDonald M R MR Li X Y XY Virgin H W HW
Journal of virology 19970201 2
A gene (HJ1) present in murine cytomegalovirus (MCMV) encodes an open reading frame (ORF) whose predicted amino acid sequence shows homology to the beta (or C-C) class of chemotactic cytokines known as chemokines. The region of homology is located in the carboxyl-terminal portion of the 116-amino-acid ORF. A 0.9-kb RNA transcript corresponding to the HJ1 gene is expressed in MCMV-infected fibroblasts and macrophages as a member of the late kinetic class of virally encoded transcripts. A transcri ...[more]