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Establishing the robustness of short-tandem-repeat statistics for forensic applications.

ABSTRACT: Before the introduction of a four-locus multiplex short-tandem-repeat (STR) system into casework, an extensive series of tests were carried out to determine robust procedures for assessing the evidential value of a match between crime and suspect samples. Twelve databases were analyzed from the three main ethnic groups encountered in casework in the United Kingdom: Caucasians, Afro-Caribbeans, and Asians from the Indian subcontinent. Independence tests resulted in a number of significant results, and the impact that these might have on forensic casework was investigated. It is demonstrated that previously published methods provide a simple procedure for correcting allele frequencies--and that this leads to conservative casework estimates of evidential value.

SUBMITTER: Evett IW

PROVIDER: S-EPMC1914534 | biostudies-other | 1996 Feb

REPOSITORIES: biostudies-other

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Establishing the robustness of short-tandem-repeat statistics for forensic applications.

Evett I W IW Gill P D PD Scrange J K JK Weir B S BS

American journal of human genetics 19960201 2

Before the introduction of a four-locus multiplex short-tandem-repeat (STR) system into casework, an extensive series of tests were carried out to determine robust procedures for assessing the evidential value of a match between crime and suspect samples. Twelve databases were analyzed from the three main ethnic groups encountered in casework in the United Kingdom: Caucasians, Afro-Caribbeans, and Asians from the Indian subcontinent. Independence tests resulted in a number of significant results ...[more]

PMID: 8571967

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