Ontology highlight
ABSTRACT:
SUBMITTER: Hansen LM
PROVIDER: S-EPMC192782 | biostudies-other | 1993 Dec
REPOSITORIES: biostudies-other
Antimicrobial agents and chemotherapy 19931201 12
The tetracycline resistance determinant on plasmid pVM111 from an avian strain of Pasteurella multocida mediates tetracycline resistance by a regulated active efflux mechanism. DNA coding for the determinant did not hybridize at high stringency with DNA representing a group of common tetracycline resistance determinants. The DNA sequence, however; revealed a structural gene and a repressor gene which had significant (37 to 64%) sequence similarities with previously described classes of efflux-ty ...[more]