Molecular cloning and characterization of the pgm gene encoding phosphoglucomutase of Escherichia coli.
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ABSTRACT:
SUBMITTER: Lu M
PROVIDER: S-EPMC196791 | biostudies-other | 1994 Sep
REPOSITORIES: biostudies-other
Publications
Molecular cloning and characterization of the pgm gene encoding phosphoglucomutase of Escherichia coli.
Journal of bacteriology 19940901 18
We report here the identification and characterization of pgm, a gene in Escherichia coli that encodes the enzyme phosphoglucomutase, specifically required for the catalysis of the interconversion of glucose 1-phosphate and glucose 6-phosphate. The predicted amino acid sequence of the pgm gene is highly conserved in E. coli, Acetobacter xylinum, Saccharomyces cerevisiae, rabbits, and humans. pgm deletion mutant strains are deficient in phosphoglucomutase activity. ...[more]
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