Ontology highlight
ABSTRACT:
SUBMITTER: Doyle ME
PROVIDER: S-EPMC1988872 | biostudies-other | 2007 Oct
REPOSITORIES: biostudies-other
Doyle Máire E ME Boggs Lori L Attia Robert R Cooper Lauren R LR Saban Daniel R DR Nguyen Cuong Q CQ Peck Ammon B AB
The American journal of pathology 20070906 4
Sjögren's syndrome (SjS) is a human autoimmune disease characterized by exocrine dysfunction resulting from chronic autoimmune attack primarily against the lacrimal and/or salivary glands. Although, we previously established a good correlation between SjS in humans and autoimmune exocrinopathy in NOD/LtJ mice an in-depth evaluation of lacrimal gland disease in the NOD/LtJ mouse has remained limited. This leaves a major gap in our understanding of the dacryoadenitis/keratoconjunctivitis sicca in ...[more]