Ontology highlight
ABSTRACT:
SUBMITTER: Groisman EA
PROVIDER: S-EPMC205741 | biostudies-other | 1992 Jan
REPOSITORIES: biostudies-other
Groisman E A EA Heffron F F Solomon F F
Journal of bacteriology 19920101 2
We have cloned the Escherichia coli phoP gene, a member of the family of environmentally responsive two-component systems, and found its deduced amino acid sequence to be 93% identical to that of the Salmonella typhimurium homolog, which encodes a major virulence regulator necessary for intramacrophage survival and resistance to cationic peptides of phagocytic cells. The phoP gene was mapped to kilobase 1202 on the Kohara map (25-min region) of the E. coli genome (Y. Kohara, K. Akiyama, and K. I ...[more]