Ontology highlight
ABSTRACT:
SUBMITTER: Guillon JM
PROVIDER: S-EPMC206212 | biostudies-other | 1992 Jul
REPOSITORIES: biostudies-other
Guillon J M JM Mechulam Y Y Schmitter J M JM Blanquet S S Fayat G G
Journal of bacteriology 19920701 13
In bacteria, as well as in chloroplasts and mitochondria, the free amino group of the methionylated initiator tRNA(fMet) is specifically modified by the addition of a formyl group. The importance of this modification remains unclear. With the availability of pure Escherichia coli 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase, the enzyme catalyzing Met-tRNA(fMet) formylation, the corresponding fmt gene and its flanking regions were cloned and sequenced. The chromosomal fmt ...[more]