Ontology highlight
ABSTRACT:
SUBMITTER: McConnell RE
PROVIDER: S-EPMC2064212 | biostudies-other | 2007 May
REPOSITORIES: biostudies-other
The Journal of cell biology 20070514 4
Microvilli are actin-rich membrane protrusions common to a variety of epithelial cell types. Within microvilli of the enterocyte brush border (BB), myosin-1a (Myo1a) forms an ordered ensemble of bridges that link the plasma membrane to the underlying polarized actin bundle. Despite decades of investigation, the function of this unique actomyosin array has remained unclear. Here, we show that addition of ATP to isolated BBs induces a plus end-directed translation of apical membrane along microvil ...[more]